血栓通治疗糖尿病视网膜病变的眼血流动力学超声多普勒检测评估  

CDI evaluation DR treatment with using Xueshuantong complex capsule

作　　者：蔡晓华[1] 王洁婷[1] 何伟珍[1] 黄力[1] 

机构地区：[1]深圳市福田区人民医院眼科,518033

出　　处：《临床眼科杂志》2004年第6期533-535,共3页Journal of Clinical Ophthalmology

摘　　要：目的　应用彩色多普勒超声仪评价复方血栓通胶囊治疗糖尿病视网膜病变的疗效。方法　对 5 0例糖尿病视网膜病变 (diabetic retinopathy,DR)患者 ,在基础治疗不变的情况下 ,给予复方血栓通胶囊 3粒 /次 ,3次 /天 ;治疗持续 3个月 ,3个月为一疗程。利用彩色多普勒超声仪 (color Doppler imagining,CDI)观察该组病例治疗前后眼动脉的各项血流动力学指标、同时观察视力及眼底变化。结果　糖尿病视网膜病变患者用药后总有效率达88% ,视力提高或稳定 ,眼底病变稳定 ,血流动力学指标有明显改善 (P <0 .0 1) :眼动脉收缩期峰值血流速度(Psv)、舒张末期血流速度 (Edv)、平均血流速度 (Vm)显著增高 ,阻力指数 RI和搏动指数 PI均降低。结论　复方血栓通胶囊对糖尿病视网膜病变有较好的治疗效果 ;超声多普勒技术是评价其药物疗效的无创性、敏感性的方法。Objective Inspected by color Doppler imagining (CDI), to evaluate the effect of diabetic retinopathy (DR) treatment with Xueshuantong complex capsule.Methods 50 DR patients with basic therapy, using Xueshuantong complex capsule three months successively, three times a day, three granulations each time. Inspected by CDI, observe the changes of sight, fundus oculi and ocular hemodynamics in the eyes of those patients before and after the treatment.Results Sight of patients(88%) was raised or stabilized, lesion of fundus oculi stabilized. There was a significant improvement in the ocular hemodynamics(P<0.01). Psv, Edv and Vm were significantly increased in ophthalmic artery, but RI and PI were decreased. Conclusion Xueshuantong complex capsule is effective for treating DR. CDI is a significant technique for diagnosing early DR and a sensitive index to evaluate the treatment effect.

关 键 词：治疗 糖尿病视网膜病变 血流动力学 复方血栓通胶囊 眼动脉 彩色多普勒超声仪 血流速度 眼底病变 峰值 超声多普勒 

分 类 号：R774.1[医药卫生—眼科]