MR灌注成像在脑胶质瘤术前分级中的价值  

Value of perfusion-weighted MR imaging in the preoperative grading of cerebral glioma

作　　者：杨伊林[1] 邢伟[2] 邵耐远[1] 彭亚[1] 徐寿良[2] 俞胜男[2] 

机构地区：[1]常州市第一人民医院神经外科,江苏213003 [2]常州市第一人民医院影像科,江苏213003

出　　处：《放射学实践》2004年第12期896-898,共3页Radiologic Practice

基　　金：常州市科技局基金资助 (常科发 0 3 88)

摘　　要：目的 :运用磁共振灌注成像 (PWI)技术 ,探讨脑血流容量 (rCBV)及其rCBV比值在脑胶质瘤术前分级中的价值。方法 :3 2例经病理证实的脑胶质瘤 ,其中Ⅰ级 2例 ,Ⅱ级 9例 ,Ⅲ级 14例 ,Ⅳ级 7例 ,行PI扫描 ,计算肿瘤最大rCBV及其rCBV比值 ,将结果与病理分级进行对照。结果 :低分级胶质瘤rCBV值为 43 .82± 15 .5 1,rCBV比值为 2 .89± 0 .83 ;高分级胶质瘤rCBV值为 12 4.3 2± 3 0 .5 4,rCBV比值为 7.82± 1.2 1;两组的rCBV值以及rCBV比值差异均有显著性意义 (P <0 .0 0 1)。结论 :不同分级的胶质瘤之间的rCBV及rCBV比值差异存在显著性意义 ,PWI技术有助于脑胶质瘤的术前分级。Objective:To evaluate the potential of rCBV and rCBV ratio in the grading of cerebral gliomas by perfusion weighted MR imaging (PWI).Methods:MR PWI was performed in 32 patients with cerebral glioma,including 11 cases of low-grade (grade Ⅰ～Ⅱ) and 21 cases with high-grade (grade Ⅲ～Ⅳ) glioma.The perfusion data were deconvoluted to get a map of rCBV.The maximal rCBV and rCBV ratio of each lesion was correlated with histopathologic grading of gliomas.Results:The rCBV and rCBV ratio in low-grade gliomas were 161.51±60.69 and 2.89±0.83 respectively,but 506.13±157.89 and 5.96±2.47 in high-grade glioma.There was significant difference in rCBV (P<0.001) and rCBV ratio (P<0.001) between the low-grade and high grade glioma.Conclusion:Significant difference in rCBV and rCBV ratio exists between gliomas of different grade.Perfusion weighted MR imaging is very useful in pre-operative grading of cerebral gliomas.

关 键 词：神经胶质瘤 磁共振成像 脑肿瘤 

分 类 号：R739.4[医药卫生—肿瘤]