人晶体总蛋白质中的43KD多肽  

THE 43KD POLYPEPTIDE IN THE PROTEINS OF HUMAN LENS

作　　者：曹心嫄[1] 陈又昭[1] 梁舜薇[1] 黄强[1] 李绍珍[1] 毛文书[1] 

机构地区：[1]中山医科大学中山眼科中心

出　　处：《眼科学报》1993年第4期183-185,共3页Eye Science

摘　　要：本文使用S.D.S—聚丙烯酰胺凝胶电泳对人胚胎、青年、成年透明晶体及老年性白内障晶体囊上皮、皮质和核三部分的总蛋白质可溶性和脲溶性蛋白质进行了测定,发现在囊上皮部分自胎儿到老年性白内障晶体均有一条43KD多歇.而自14岁开始在晶体皮质及核的可溶性蛋白质中这条43KD多肽带明显加宽.在晶体皮质及核的碌溶性蛋白中这条谱带随年龄增长变得模糊.在老年性白内障晶体中则几乎消失.The total proteins, water-soluble proteins and the urea-soluble proteins of the lens from fetal, adult and senile cataract were determined by SDSPAGE. It was found that there was a 43KD polypeptide in the capsular-epithelium of all lens stated above. The band on SDS-PAGE corresponding to 43KD polypetide was wide in the water-soluble proteins of the cortex and nucleus of the lenses obtained from over 14-year-old individuals. It became blurred in the urea-soluble proteins of cortex and nucleus of lens with aging, whereas it became almost disappeared in the senile cataract lens.

关 键 词：晶体蛋白 晶体 白内障 

分 类 号：R776.102[医药卫生—眼科] Q51[医药卫生—临床医学]