对大鼠肠道菌群有调整作用的中药筛选  

Screening the traditional Chinese medicine with modulating function in rat intestinal flora

作　　者：史权[1] 薛艳华[2] 赵光远 杨景云[2] 马淑霞[2] 李俭[2] 李立秋[2] 聂清[2] 刘君兴[2] 施中凯[2] 宋淑贤[2] 

机构地区：[1]佳木斯大学化学与药学院,黑龙江佳木斯154007 [2]佳木斯大学基础医学院,黑龙江佳木斯154007 [3]哈尔滨市骨伤科医院,黑龙江哈尔滨150000

出　　处：《黑龙江医药科学》2005年第1期28-30,共3页Heilongjiang Medicine and Pharmacy

摘　　要：目的:筛选对大鼠肠道菌群有调整作用的中药。方法:本实验利用盐酸林可霉素制备大鼠肠道菌群失调模型,选择补益类中药三补、肉苁蓉、香砂六君子汤、三泻进行肠道菌群调整。结果:发现补益类中药均具有一定程度调整菌群失调的作用,其中中药三补疗效最佳,且其对大鼠肠道菌群的调整作用明显优于丽珠肠乐阳性对照组。结论:补益类中药均具有一定程度调整菌群失调的作用,具有扶正固本的功效,起到益生元的作用,三补尤为显著。Objective: To screen a group of traditional Chinese medicines with modulating function in rat intestinal flora. Method: This experiment used Lincomycin Hydrochloride to prepare the rat intestinal flora dysbacteriosis model, and selected tonic traditional Chinese medicine SanBu, Herba Cistanches, Xiang ShaLiuJunZiTang and San Xie to modulate the rat intestinal flora . Results: All the tonic traditional Chinese medicine has a certain modulation in dysbacteria, with the best curative effect of SanBu among them, and San Bu was obviously superior to LiZhuChangLe of positive contrast group in the rat intestinal flora modulating function. Conclusion: Tonic traditional Chinese medicine SanBu, has supporting the healthy energy effect, played prebiotics function .

关 键 词：菌群失调 肠道菌群 益生元 

分 类 号：R285.6[医药卫生—中药学]