5-(4-吡啶基)-2-芳酰氨基-1,3,4-噻二唑的合成及生物活性  

Synthesis and Biological Activities of 2-aroylamino-5-(4-pyridyl)-1,3,4-thiadiazoles

作　　者：宋新建[1] 谭小红[1] 桑秋章[1] 余爱农[1] 

机构地区：[1]湖北民族学院化学与环境工程学院,湖北恩施445000

出　　处：《湖北民族学院学报（自然科学版）》2005年第1期79-81,共3页Journal of Hubei Minzu University(Natural Science Edition)

基　　金：湖北省教育厅重大项目资助(2001Z0108).

摘　　要：利用2-氨基-5-(4-吡啶基)-1,3,4-噻二唑和取代苯甲酰氯的酰化反应,合成了6个5-(4-吡啶基)-2-芳酰氨基-1,3,4-噻二唑类化合物Ⅲa～f,其结构经1HNMR、IR和元素分析方法证实.初步的生物活性测定试验表明:部分化合物具有较好的植物生长调节活性.Six derivatives of 2-aroylamino-5-(4-pyridyl)-1,3,4-thiadiazoles Ⅲa～f have been synthesized by amidation of 2-amino-5-(4-pyridyl)-1,3,4-thiadiazoles and substituted benzoyl chloride. The structures of all these compounds were confirmed by 1H NMR, IR and elementary analysis. It is found from the results of preliminary biological activity tests that some of the target compounds have a good activity on plant growth regulating.

关 键 词：芳酰氨基 1 3 4-噻二唑 合成 植物生长调节活性 

分 类 号：O625.632[理学—有机化学]