动词特异性损伤的原发性进行性失语个案  

A primary progressive aphasic patient with verb specific deficits

作　　者：韩在柱[1] 舒华[1] 张玉梅[2] 周筠[2] 

机构地区：[1]教育部认知与学习重点实验室,北京师范大学心理学院,北京市100875 [2]北京天坛医院神经内科,北京市100050

出　　处：《中国临床康复》2005年第4期58-59,共2页Chinese Journal of Clinical Rehabilitation

基　　金：攀登计划项目(95-专-09);教育部科学技术重点项目(01011);国家自然科学基金资助项目(30070259)~~

摘　　要：目的:探讨1例汉语原发性进行性失语个案,及其表现出的动词特异性损伤现象,揭示该病与动-名词分离间的可能关系,从而为临床诊断和康复治疗提供一定的理论依据。方法:2004-03对北京天坛医院神经内科1例就诊患者采用两组神经心理学测验,从多任务、多角度考察患者是否存在动-名词的认知分离。结果:患者在阅读和图/词匹配任务中动、名词的作业成绩无明显差异,而图形写名时对名词的书写正确率(53%)显著高于动词(18%)(χ2=9.273,P<0.001),即使依次控制了一些影响因素后,对名词的正确率(32%～43%)仍然高于动词(14%)(P均<0.001)。结论:该病例为动词特异性损伤原发性进行性失语。AIM:To investigate a patient with primary progressive aphasia(PPA) and his performance of verb specific deficits and reveal the possible relationship between PPA and verb noun dissociation so as to provide some theoretical proof for clinical diagnosis and rehabilitation of the disease.METHODS:One patient was selected as the subject from Department of Neurology,Beijing Tiantan Hospital in March 2004.Two typical neuropsychological tests involving many tasks from multiple points of views were used to examine whether the patient presented verb noun dissociation.RESULTS:No obvious verb noun difference occurred in the patient's oral reading and visual word/picture matching.However,in written picture naming task,he showed significantly higher correct ratio of nouns(53%) than that of verbs(18%)(χ2=9.273,P< 0.001).Furthermore,after some important confounding factors were controlled,his written picture naming remained higher accurately in noun items(32%to 43%) than verb ones(14%)(all P< 0.001).CONLUSION:The patient was a PPA case with verb specific deficits.

关 键 词：失语 原发进行性 神经心理学测验 认知 

分 类 号：R749[医药卫生—神经病学与精神病学]