顽固性癫痫患者甲襞微循环的临床研究  

The clinic study of nail microcirculation on stubborn epileptic

作　　者：屈洪党[1] 陈开地[1] 王学德[1] 

机构地区：[1]安徽省蚌埠医学附属医院

出　　处：《现代康复》1998年第10期1100-1101,共2页Modern Rehabilitation

摘　　要：目的：探讨山茛菪硷治疗顽固性癫痫（ＥＰ）患者的作用机理。方法：通过与３０名正常人对照，观察５０例ＥＰ患者经山莨菪硷治疗前后甲襞微循环各项指标的异常率。结果：ＥＰ患者与正常人比较，甲襞微循环各指标异常率均明显高于正常对照组（Ｐ＜０．０１）；ＥＰ患者治疗前也显著高于治疗后（Ｐ＜０．０１）。结论：癫痫病患者有明显的微循环障碍；经用山茛菪硷治疗后明显改善，临床症状明显好转，表明该药治疗本病的作用机理为改善微循环，增加其血液灌注量，促进脑功能恢复。本研究提示，脑微循环障碍可能是顽固性癫痫的重要发病机理和难治因素之一。Abstract Aim:To study the mechanism that anisodaminum cure stubborn epileptic.Method:Abserve the abnormal rate of nail Microcirculation’s several indicators among 50 epileptic comparing with normal 30 persons.Result:The abnormal rate epileptic nail microcirculation’s several indicators is singificantly higher than that of normal control group(P<0.01) and before treatment the rate is also higher than that after treatment(P<0.01).Conclusion:Anisodaminum can ameliorate the microcirculation of brain,increase the blood infusing to the brain,promote the brain function recovery and alleviate the clinic symptom.

关 键 词：顽固性癫痫 甲襞微循环 山莨菪硷 药物治疗 

分 类 号：R742.1[医药卫生—神经病学与精神病学]