经肠道摄入精氨酸对胃癌手术患者免疫功能的影响  

The effects of postoperative arginine intake on the immune function of gastric cancer patients

作　　者：彭承宏[1] 彭淑牖[1] 苏英[1] 江献川[1] 方河清[1] 

机构地区：[1]浙江医科大学附属第二医院外科,杭州310009

出　　处：《中国胃肠外科杂志》1998年第2期88-90,共3页

摘　　要：目的观察术后早期肠道摄入精氨酸对胃癌根治术患者免疫功能的作用。方法以40例胃癌根治术患者为研究对象。患者术后随机分为四组。两组术后早期经PS管每天输注精氨酸液,剂量分别为15g/d和30g/d,共7天。同时检测 T 淋巴细胞亚群、自然杀伤细胞活性、免疫球蛋白、补体 C3和迟发皮肤超敏反应。结果不同剂量的精氨酸对胃癌患者术后均有一定的免疫促进作用,而精氨酸30g/d 组可能达到更好的免疫反应状态。结论术后早期经肠道给予精氨酸对胃癌患者术后免疫功能有增强作用。Objective To observe the immune effects of enteral arginine intake in gastric cancer pa- tients after radical operation.Methods 40 gastric cancer patients having radical gastroectomy were involved. The patients were randomly divided into four groups.Two groups received arginine by PS tube feeding from the day 0 to day 7 after operation in the early stage.The doses of arginine were 15g/d and 30g/d respec- tively.T-lymphocyte subpopulation,NKC,immunoglobulin,complement C3 and DTH were measured.Re- sults Both dose of arginine taken could improve host immtmity.Enteral nutrition with arginine 30g/day may have had better immune response.Conclusions The enteral arginine intake immediately after operation can improve immune function of gastric cancer patients postoperatively.

关 键 词：肠道摄入 精氨酸 胃癌 手术治疗 免疫功能 细胞活性 肿瘤 消化系统 

分 类 号：R735.2[医药卫生—肿瘤]