老年急性非淋巴细胞白血病的临床特征  

A STUDY FOR ACUTE NONLYMPHOCYTIC LEUKEMIA IN ELDERLY PATIENTS

作　　者：潘祖玉[1] 赵沄[1] 胡允平[1] 

机构地区：[1]华东医院血液科,上海市200040

出　　处：《老年医学与保健》1996年第2期70-72,共3页Geriatrics & Health Care

摘　　要：本文观察了14例老年急性非淋巴细胞白血病(ANLL)的临床特点,中位年龄70岁,继发于MDS的ANLL 4例;接受化疗12例,其中仅3例进行2个疗程HOAP方案化疗,完全缓介(CR)只有1例,老年急性白血病患者脏器功能减退,常患有多种慢性疾病,对化疗耐受性降低;继发白血病多见,这些可能是导致老年ANLL低缓介率、高死亡率的因素。作者认为加强支持措施是提高老年ANLL的缓介率,延长缓介期的关键。The clinical features of acute nonlymphocytic leukemia (ANLL) in 14 elderly patients, the middle-point age was 70 years, which included 4 cases of ANLL secondary to myelodysplastic syndrome (MDS) were reviewed. Twelve cases had recieved chemotherapy, merely three cases with HOAP therapy for two course, but only one case complete remission. Impairment of visceral function were observed in all the patients. The toleration of chemotherapy of the patients were significantly decreased because of suffering from multiple chronic diseases, and secondary leukemia appeared frequently. These factors led to lower complete remmission and higher mortality. It is believed that intensive supporting measures may increase CR of ANLL in the elderly patients and prolong the remission period.

关 键 词：老年 ANLL 急性非淋巴细胞白血病 继发 临床特征 化疗 HOAP方案 作者 支持 因素 

分 类 号：R733[医药卫生—肿瘤]