补肾中药对SRBC免疫后大鼠脑和免疫组织中β和M受体功能的影响  

The effect of kidney-benefiting chinese herbal medicine on the function of neurotransmitters receptors in brain and immunizing organ after immunized rats using SRBC

作　　者：宫斌[1] 莫志红[1] 莫启忠[1] 游洪[1] 方军[1] 陈坤华[1] 徐多为 

机构地区：[1]上海中医学院核医学研究室,上海200032

出　　处：《中国免疫学杂志》1993年第6期377-380,共4页Chinese Journal of Immunology

基　　金：国家自然科学基金资助课题

摘　　要：用受体放射性配基结合分析法(RLBA)测定了由SRBC 免疫后正常青年大鼠脑不同分区组织、脾脏(简称Spl)和胸腺(简称Th)中的β和M 受体的结合容量(Rt)。实验结果表明:在SRBC 免疫之后,大鼠大脑皮层(简写Cer.)、Th 和Spl 组织中的β和M 受体的Rt 值均明显降低,西药、中药和补肾中药可使降低了的β和M 受体Rt 值有不同程度升高,其中补肾中药作用最好。在海马(简写Hip.)和纹状体(简写Str.)组织中,SRBC 免疫后M 受体的Rt 值有降低和升高趋势,但差异无统计意义。西药、中药和补肾中药对HiD 和Str 组织中M 受体的Rt 值无明显调整作用。It were determined to β and M receptors(Rt)of differnce brain area,spleen and thymusafter immunized adult rats using SRBC with receptor radioligand binding assay(RLBA).Theresults showed that β and M receptors were decreased obviously in cerebral cortex(Cre.)thy-mus(Th.)and spleen(Spl.)after immunized rats using SRBC.Drugs groups including westmedicine,chinese herbal medicine(CHM)and kidney-benefiting chinese herbal medicine(KBCHM)have promoted obviously differently degree on have decreased β and M receptors Rtin Cer.Th.and Spl.after immunized rats using SRBC,but the effection of KBCHM was best.After immunized rats using SRBC,M receptor Rt in hippocampus(Hip.)and striaum(Str.)has decreaded or raised tending,but it were not statistic significance,Those drugs includingwest medicine,CHM and KBCHM don't have regulation for M receptor Rt in Hip.and Str.

关 键 词：受体 补肾 中药 免疫组织 免疫学 

分 类 号：R229[医药卫生—中医基础理论]