介入治疗联合多因子灌肠治疗中晚期直肠癌的随机研究  

Evaluation of Intervention Therapy Combined with Multifactors Enema In Treating Developing and Advanced Rectal Cancers

作　　者：王炳胜[1] 王丽玲[1] 王义清[2] 付显成[1] 赵增虎[1] 

机构地区：[1]河北省张家口第251医院中医肿瘤科,张家口075000 [2]西安市第四军医大学唐都医院介入放射科,西安710038

出　　处：《中国临床医学》2001年第1期36-38,共3页Chinese Journal of Clinical Medicine

摘　　要：目的 :探讨中晚期直肠癌非手术的治疗方法。方法 :5 6例患者随机分成两组 :(1)对照组 :单用动脉灌注化疗。 (2 )综合治疗组 :采用动脉灌注化疗、栓塞同时用 5 -FU、锡类散、云南白药等多因子灌肠治疗。两组病人行两次介入治疗。结果 :两组有效率 ,平均缓解期 ,中位生存期 ,1、2年生存率分别为 32 .7%、6 0 .7% ,2 .8个月、5 .1个月 ,6 .5个月、11个月 ,32 .7%、6 4.3 % ,3 .6 %、2 1.4%。两组差异显著 (P <0 .0 5 ) ,两组临床症状改善也有显著差异 (P <0 .0 5 )。结论 :综合治疗可有效延长晚期直肠癌患者生存期 ,并改善其生存质量。Objective: To study management for developing or advanced retum cancer without operation. Methods: Fifty six patients were randomly devided into two groups. In control group (A): with only interventional chemotherapy, in the combination treatment group (B): with arterial inteventional chemotherapy and embolizalion and enema with 5-FU, Xileisan, Yunnanbaiyao. Interventional chemotherapy were used twice in two groups for twice. Results: The effective, mean remission period, median survival times, 1-year, 2-year survival rates in group A and B were 32.7?%, 60.7?%; 2.8?months, 5.1?months, 6.5?months, 11?months; 32.7?%, 64.3?%, 3.6?%, 21.4?%, respectively. There were significant difference between them. Clinical symptom was improved differently in two groups ( P <0.05). Conclusion: The combination treatment can effectively prolong the survival times of patient with advanced rectum cancer and improve the life quality of patients obviously.

关 键 词：灌肠治疗 直肠癌 介入治疗 中晚期 随机研究 患者 联合 改善 平均 目的 

分 类 号：R735[医药卫生—肿瘤] R734[医药卫生—临床医学]