紫外分光光度法测定尿中环丙沙星的排泄量  

Determination of ciprofloxacin output in urine by UV—spectrophotometric method

作　　者：张华安[1] 张秋霞[1] 封卫毅[1] 

机构地区：[1]西安医科大学第一临床医学院,710061

出　　处：《中国医院药学杂志》1993年第3期116-117,共2页Chinese Journal of Hospital Pharmacy

摘　　要：本文采用紫外分光光度法测定尿液中环丙沙星(iprofloxacin 环丙氟哌酸)的排泄量,尿样用0.01mol/L NaOH 液稀释,在335nm 波长处直接测定吸收度,平均回收率为100.0%,CV=0.76%(n=9),6例受试者环丙沙星的尿药总排泄量为给药量的61%。The ciprofloxacin output in urine was determined by UV-spetrophotometrie method.Urine was diluted with 0.01mol/Lsodium hydroxide.Ciprofloxacin was analyzed at 335nm.Average recovery was 100.0% and cv was 0.76%(n=9).Theciprofloxacin output in urine of 6 cases accounted for 61.0% of total dose of oral administration.

关 键 词：环丙沙星 分光光度法 尿 排泄量 

分 类 号：R914.1[医药卫生—药物化学]