垂体催乳素微腺瘤经蝶手术与溴隐亭治疗后CT及内分泌变化  

Changes of CT scan and prolactin of prolactin secreting microadenomas after treatment

作　　者：宁可 陈明振[2] 卢丽霞[3] 蔡纪辕[2] 姚树勋[2] 

机构地区：[1]广州珠江医院神经外科,510282 [2]中山医科大学附属一院脑外科 [3]中山医科大学附属肿瘤医院CT

出　　处：《中华神经外科杂志》1993年第3期147-149,共3页Chinese Journal of Neurosurgery

摘　　要：本文报告78例垂体催乳素微腺瘤治疗后 CT 及内分泌变化。其中男2例,女76例,平均年龄30.6岁,治疗前催乳素均高于正常,CT 扫描均有垂体内低密度病灶(<10mm)。32例经蝶手术,术后25例催乳素恢复正常;CT 复查肿瘤消失28例,缩小4例;46例服溴隐亭治疗,19例催乳素恢复正常,CT 复查肿瘤消失1例,缩小3例,不变33例,增大9例。对垂体催乳素微腺瘤的疗效问题进行讨论。The change of CT scan and prolactin(PRL)deter-mination were studied in 78 PRL microadenomas.There were 76 females and 2 malel.Mean age was30.6 years.PRL was higher than normal level in allpatients before treatment.All tumors were lower den-sity in CT scan and their diameter were less than10mm.32 PRL microadenomas were removedtranssphenoidally by microsurgery.The follow-up pe-riod was 5 months～3 years.PRL level restored tonormal in 25 cases(78%).CT scan showed tumor dis-appeared in 28 cases,shrinked in 4 cases.46 patientswere treated by oral bromorcriptine for 3～6 months.PRL level restored normal in 19 cases(41%).CT scanshowed tumor disappeared in one case,shrinked in 3cases,unchanged in 33 cases and enlarged in 9 cases.The therapeutic efficiency of PRL microadenoma is dis-cussed.

关 键 词：垂体肿瘤 显微外科学术 溴隐亭 

分 类 号：R736.4[医药卫生—肿瘤]