41例自体造血干细胞移植治疗白血病及其他恶性肿瘤临床研究  

Clinical Studies of Autologous Hematopoietic Stem Cell Transplantation in 41 Patients with Leukemia and Other Malignant Diseases

作　　者：刘海川[1] 姚善谦[1] 彭矞云[1] 吕善根[1] 楼方定[1] 王连元[1] 刘景汉[1] 刘作斌[1] 汪月增[1] 周绮[1] 朱军[1] 阎影[1] 吴祖泽 裴雪涛 马恩普 

机构地区：[1]解放军总医院 [2]军事医学科院

出　　处：《军医进修学院学报》1993年第3期162-164,共3页Academic Journal of Pla Postgraduate Medical School

摘　　要：本文报告ABMT8例、PABMT15例、ABHSGT18例,治疗白血病35例、淋巴瘤4例骨髓瘤和神经母细胞瘤各1例。经预处理强有力的放疗化疗后移植。其骨髓造血功能恢复分别为60天、53天和29.5天。提示ABHSGT组恢复最快。其复发率及无病生存率分别为37.5％、30％、18.7％和75％、73.4％、72.3％。而同期化疗组复发率及无病生存率分别为76.4％和32.5％。提示ABMT组、PABMT组、ABHSCT组疗效明显优于化疗组。41 patients (35 leukemias, 4 lymphomas, 1 myeloma and 1 neuroblastoma)were treated by ABMT without purgint, 15 patients treated by PABMT with purging and 18 patients treated by ABHSCT. The results indicated that the ABHSCT had a earlier hematopoietic reconstitution, lesser complications and a lower relapse rate. Comparing with the conventional chemotherapy, all three transplant groups had an obviously longer disease-free survival time and a better curative effect.

关 键 词：造血干细胞 移植 白血病 治疗 骨髓植移 

分 类 号：R733.7[医药卫生—肿瘤]