15例血管外皮瘤的临床病理及免疫组化观察  

Clinicopathologic and Immunohistochemical Observations on 15 cases of Hemangiopericytoma

作　　者：李蜀华[1] 陈代云[1] 赵方[1] 郑敏[2] 

机构地区：[1]华西医科大学病理学教研室,成都610041 [2]成都市第三人民医院,610000

出　　处：《临床与实验病理学杂志》1993年第1期14-16,T005,共4页Chinese Journal of Clinical and Experimental Pathology

摘　　要：通过光镜、网织纤维及免疫组化染色对15例血管外皮瘤进行了研究,其诊断要点为:(1)血管极为丰富,遍布整个肿瘤组织,而呈非灶性区域性的血管外皮瘤样区,血管腔隙大小不等、形状不一,从大的扩张薄壁血窦、鹿角状血管,到中等大小直至小的毛细血管均可见到;(2)网织纤维极为丰富,遍布全瘤,且分布规律,总在血管基底膜外围绕单个或2～3个瘤细胞呈细网状,瘤细胞巢内均有网织纤维;(3)免疫组化染色瘤细胞仅对Vimentin呈阳性反应。本文还讨论了与滑膜肉瘤等的鉴别诊断。Fifteen cases of hemangiopericytoma were studied by light-microscopically using reticulinand immunohistochemical stainings.The results suggest that the main points in diagnosis are:1.Theblood vessels were very abundant and showed a consistent hemangiopmericytoma pattern throughoutthe tumor,but not limited in focal or regional hemangiopericytoma-like areas as seen in other sarco-mas.The lumen of blood vessel varied markedly ranging from large ectatic thin-walled blood sinuses tomiddle blood vessels and small-sized capillariies.2.A rich meshwork of reticulin fibers surroundingsmall groups or single tumor cells outside the basement membrane of blood vessels were prominentlydisplayed.3.In immunohistochemical stainings the tumor cells reacted positively only to vimentim.Thedifferential diagnosis from other sarcomas,particularly from synovial sarcoma was also discussed.

关 键 词：血管外皮瘤 滑膜肉瘤 角质蛋白 

分 类 号：R732.202[医药卫生—肿瘤]