小剂量辐射照后小鼠胸腺细胞增殖的形态学观察  

ENHANCED EFFECTS OF LOW DOSE RADIATION ON THE PROLIFERATIVE ACTIVITY OF THYMOCYTES IN MICE

作　　者：李修义[1] 刘洪宇[1] 吕哲[1] 张迎春[1] 刘树铮[1] 

机构地区：[1]白求恩医科大学放射生物教研室

出　　处：《辐射研究与辐射工艺学报》1994年第2期124-126,共3页Journal of Radiation Research and Radiation Processing

基　　金：国家自然科学基金

摘　　要：７５ｍＧｙＸ射线全身照射Ｃ５７ＢＬ／６小鼠．发现照射后３、４和７ｄ，胸腺皮质、皮髓交界和髓质区内处于有丝分裂相的胸腺细胞百分数均明显高于对照组，而发生核固缩的胸腺细胞百分数与对照组比较均无明显差异。本实验结果从胸腺细胞形态学角度进一步证实了小剂量电离辐射确有增强胸腺细胞增殖活性的作用。C 57 BL/6 mice were whole-body irradiated (WBI) with 75 mGy X-rays. The percentage of the mitotic thymocytes in the area of cortex, medulla as well as the boundary in thymus was significantly higher than that in the sham-irradiated control 3 to 7 days after irradiation. At the same time there were no significant differences in the percentage of pyknotic thymocytes in the areas mentioned above compared with the control. The present study on thymocyte morphology demonstrated further that low dose radiation may enhance the proliferative activity of thymocytes.

关 键 词：胸腺细胞 有丝分裂 小剂量 辐射 

分 类 号：R811.5[医药卫生—放射医学]