胆汁返流对胃粘膜表面pH影响的检测与分析  

ANALYSIS ON RELATIONSHIP OF REFLUX OF BILE TO MUCOSA SURFACE PH IN STOMACH

作　　者：焦炳忠[1] 甄承恩[1] 刘庆熠[1] 

机构地区：[1]河北医学院,河北省医院,河北医学院附属四院

出　　处：《内镜》1994年第6期326-327,共2页

摘　　要：本研究应用ＳｃｈｏｔｔｐＨ－ＭｅｔｅｒＣＧ（８１７）和ＭＩ－５０６微型玻璃电极，在内镜直视下测量了８８例受检者的三个解剖部位共１２个位点胃粘膜表面的ｐＨ（Ｓ－ｐＨ）。又据受检者在检查过程中是否发生胆汁返流分为２组，并按解剖学位点对数据进行分析。结果表明：１．相同解剖学部位，如胃窦、角或体部的大、小弯和前、后壁的４个位点的Ｓ－ｐＨ很接近。２．胃体部粘膜的Ｓ－ｐＨ呈强酸性，ｐＨ均值约２．６；胃窦部呈弱酸性，ｐＨ约５．９。３．胆汁返流时胃体部粘膜的Ｓ－ｐＨ升高，约３．８；胃窦部约６．５，表明胆汁返流对胃体粘膜Ｓ－ｐＨ的影响大于胃窦部。The surface pH at the twelve points of gastric mucosa was seperately measured with endoscope. In the measuring process, the patients were divided into two groups according to their presence or absence of the reflux of bile. The calculation and comparison were carried out in groups. The finding shows reflux of bile could increase pH in area of secreting acid, but the pH on the angle of stomach was decreased. The incidences of mucosal atrophy, intestine metaplasia and dysplasia in the groups with reflux of bile was higher, and some questions concerned were discussed here.

关 键 词：胆汁返流 胃粘膜 PH 内窥镜 

分 类 号：R573.04[医药卫生—消化系统]