急性白血病患者血清中锰镍镉铜锌及全血中铜锌锰的研究  

STUDY ON VALUE CHANGES OF MANGANESE,NICKEL,CADMIUM,COPPER AND ZINC IN SERUM AND COPPER,ZINC,AND MANGANESE IN BLOOD IN ACUTE LEUKEMIA.

作　　者：强雅维 邵文斌[1] 翁其亮[1] 万田郎[1] 刘震[1] 

机构地区：[1]西安医科大学一附院,西安医科大学测试中心

出　　处：《山西白血病》1994年第3期142-144,共3页

摘　　要：用原子吸收光谱法测定３４例急性白血病患者和４０例正常人血清中锰（Ｍｎ）、镍（Ｎｉ）、铜（ｃｕ）、锌（ｚｎ）、镉（Ｃｄ）及全血中Ｃｕ、Ｚｎ和Ｍｎ的含量，观察到急性白血病的ＡＬＬ组和ＡＮＬＬ组患者血清、全血Ｃｕ的含量、铜锌比值（Ｃｕ／Ｚｎ）显著高于正常人（Ｐ＜０．００１）；血清、全血Ｚｎ、血清Ｍｎ含量均显著低于对照组（Ｐ＜０．００１，Ｐ＜０．０５）；血清Ｎｉ含量升高仅见于ＡＬＬ组（Ｐ＜０．０１）．血清铜含量升高与合髓白血病细胞增殖有关。he concentrations of Manganese(Mn),Nickel(Ni),cadmium(Cd),copper(Cu),and Zinc(Zn)in werum and Cu,Zn,and Mnin whole blood were determinedby atomtc absorpion sectrophotometry in34 patients with acute leukemiaand 40 normal controls. The mean values of sera Cu and blood Cuweresignificantly higher than that of the controls respectively(P<0. 00 1). The mean values of Znand Mn in serum and blood Zn were significantlylower as compared with the controls respectively(P<0.001,P<0.05).Theratio of Cu and Zn in werum was significantly higher than that ofcontrols(P<0.00 1).The increased content of sera Ni was observed Inlyin patients with acute lymphocyticleukemia. In adition,elevated sera Cucorrelated significantly with the percentage of leukemic cells in bonemarrow(P<0.01).

关 键 词：白血病 光谱法 微量元素 铜 锌 

分 类 号：R733.710[医药卫生—肿瘤]