营养因素与地方性氟骨症关系的研究  

The Relationship between Nutritional Factors and Endemic Skeletal Fluorosis

作　　者：樊继援[1] 梁雪萍[1] 尹潍[1] 廉宗澂[1] 郭世绂[1] 李锡田[2] 王笃圣[2] 臧增元 王建国 杜明瑄 周珍 

机构地区：[1]天津医科大学总医院内分泌科,放射科骨科300052 [2]天津医科大学 [3]河北省保定地区卫生防疫站 [4]河北省张家口地区地方病研究所

出　　处：《天津医药》1994年第12期713-716,共4页Tianjin Medical Journal

摘　　要：对4个饮水型高氟病区居民进行了营养与地方性氟骨症的调查。发现营养状况好的病区患者病情较轻,以早期和硬化型为主。营养状况差的病区患者病情较重,疏松和混合型多见,同时伴有血钙、磷和尿钙降低,血PTH和尿cAMP增高(P<0.05或<0.01)。研究结果提示,由于营养缺乏,特别是钙的摄入不足,可能对氟骨症的发病机制产生明显影响。Nourishment and endemic skeletal fluorosis were surveyed in 4 high fluoride drinking water villages. The investigation revealed tnat the most of patients were slight mainly in early-stage and osteosclerosis types on radiological classification in area with better nourished people, and endemic skeletal fluorosis were severe associated with X-ray types of osteoporosis in areas with inadequate nutrition where the patients' serum Ca, P, and urine Ca decreased and serum PTH, urinary cAMP increased. (P<0.05 or 0.01),The results suggested that mechanism of endemic skeletal fluorosis could be influenced by nutritional insufficency, epsecially low calcium intake.

关 键 词：氟骨症 地方性疾病 营养 钙 病理 

分 类 号：R599.902[医药卫生—内科学]