对急性脑梗死患者发病24 h内血清NSE的观察  

The Observations on NSE in Patients with Acute Cerebral Infarction within 24 Hours from Onset

作　　者：马驰骋[1] 刘爱军[1] 马英文[1] 孙涛[1] 张树民[1] 黄玉彬[1] 

机构地区：[1]山东省济南市第四人民医院内科,济南250031

出　　处：《中国临床医学》2005年第1期34-35,共2页Chinese Journal of Clinical Medicine

摘　　要：目的:观察急性脑梗死患者发病24 h内血清NSE值在不同时段的变化。方法:选取发病后24 h内入院的急性脑梗死患者82例,仔细询问发病时间,分为2-8 h、8-16 h,>16 h 3部分。与40例同期非神经系统疾病住院的患者相对照。结果: 各个时间组血清NSE水平都明显高于对照组(P<0.01),8-16 h期间血清NSE水平最高,与其它各时间组比较具有显著差异(P<0.05)。结论:急性脑梗死患者发病24 h内血清NSE水平是一个动态变化的过程,8-16Objective:To observe the changes of neuron specific enolase( NSE) in patients with acute cerebral infarction in different periods within 24 hours from onset. Methods: 82 patients with acute cerebral infarction were selected after they wen hospitalized wethin 24 hours from onset. According to the time they were ill, the patients were divided into 3 groups: 2-8 h group.8-16 h group. > 16 h group. NSE levels was compared with that of 40 patients at same period without any central nervous system diseases. Results: The serum NSE levels of each group was obviously higher than that of the control groups(P< 0.01). The serum NSE values in 8-16 h group were notably higher than that the other groups( P<0.15 ). Conclusion: It is a dynamic change course of serum NSE levels in the patients with acute cerebral infarction within 24 hours from outset. The values reach the highest degree from 8 h to 16 h after the patients were ill.

关 键 词：NSE 急性脑梗死患者 血清 发病 观察 病后 对照组 水平 目的 过程 

分 类 号：R743[医药卫生—神经病学与精神病学] R734[医药卫生—临床医学]