肺癌与肺炎衣原体感染关系的研究  

Clamydia Pneumoniae Infection and Lung Neoplasms

作　　者：周妍[1] 孙书明[2] 胡志雄[1] 金盈[1] 徐坚[2] 余竹元[3] 

机构地区：[1]复旦大学附属金山医院呼吸内科,上海200540 [2]复旦大学附属金山医院职防科,上海200540 [3]复旦大学附属中山医院内科免疫室,上海200032

出　　处：《中国临床医学》2005年第1期44-46,共3页Chinese Journal of Clinical Medicine

摘　　要：目的:研究肺炎衣原体(Cpn)和肺癌之间的关系。方法:采用间接微量免疫荧光法检测肺癌标本43例和非肺癌呼吸科病人19例肺组织中Cpn特异性抗原。结果:肺癌组Cpn抗原表达水平明显高于对照组:肺癌组中Cpn-Ag阳性率88.4%(38/ 43),对照组阳性率26.3%(5/19),p<0.0001。结论:肺癌患者易患Cpn感染,Cpn感染与肺癌有一定的关系,值得临床重视。Objective:To investigate the relationship between Chlamydia pnoumoniae(Cpn) infection and lung cancer. Methods: The Cpn-antigen was detected by microimmunofluorcscence tcchongue in 43 cases of lung cancer and 19 cases of normal lung tissue. Results:The rates of Cpn infection in patients with lung cancer were higher than those of patients without lung cancer:In lung cancer group and normal control.Cpn-Ag positive rate of were 88. 4%(38/43)and 26. 3% (5/19)respectively (p<0. 001). Conclusion: The lung cancer palicnls are liable to Cpn infection. There is a high incidence of Chlamydia pneumoniae in the patients with lung cancer. It may also play an important role in lung cancer.

关 键 词：肺癌患者 肺炎衣原体感染 对照组 阳性率 微量免疫荧光法 抗原表达 特异性抗原 目的 水平 

分 类 号：R734.2[医药卫生—肿瘤] R563[医药卫生—临床医学]