固定化酶催化合成丁酸丁酯  

Synthesise of Butyl Butyrate by Lipase on Silk Catalysis

作　　者：黄庆[1] 刘桂荣[1] 

机构地区：[1]南昌大学应用化学研究所

出　　处：《赣南师范学院学报》2004年第6期86-88,共3页Journal of Gannan Teachers' College(Social Science(2))

摘　　要：以固定化酶为催化剂,正丁醇与正丁酸为原料合成丁酸丁酯,实验考察了不同类型的酶催化剂、固定化酶催化剂用量、醇酸摩尔比、反应温度、反应时间、pH值等因素对合成酯化率的影响。优化的反应条件:醇酸摩尔比为1.5∶1.0,固定化酶催化剂用量比为0.8%,反应时间为24h,反应温度50℃,PH=7.5,酯化率可达57.3%.Butyl butyrate is synthesized by one step reaction from n～butyl alcohol and n～butyric acid, using lipase on silk as catalyst. The factors influencing the yield of product are experimentally investigated The optimum conditions are as follows∶ molar ratio of alcohol to acid 1.3∶1, catalyst amount 0.8% on the total mass of reactants, the reaction is 24h,reaction temperature50℃.pH = 7.5.Under above conditions ,the yield of butyl butyrate couldreach 57.3%.

关 键 词：固定化酶 丁酸丁酯 酯化反应 

分 类 号：O62[理学—有机化学]