不同周期光暗循环对小鼠生长的影响  

Effects of light-dark cycles on growth of mice

作　　者：江舟[1] 刘延友[1] 郭莉[1] 杨波[1] 王跃錡[1] 王正荣[1] 

机构地区：[1]四川大学华西医学中心生物医学工程研究室,四川成都610041

出　　处：《西部医学》2005年第2期97-98,101,共3页Medical Journal of West China

基　　金：国家自然科学基金资助项目 (No.39970 2 75;No.30 0 70 2 78)

摘　　要：目的　探讨不同周期光暗循环对小鼠生长的影响。方法　在不同周期的光暗循环条件下饲养小鼠。测定其活动性、生长速度及鼠粮消耗量。结果　小鼠活动性周期与光暗循环周期一致 ;在短周期的光暗循环下 ,小鼠生长速度较快 (P<0 .0 5 ) ,鼠粮消耗较多 (P<0 .0 5 ) ,长周期次之 ,而 2 4小时光暗循环生长速度最慢。结论　光暗循环能影响小鼠活动周期 ;并能影响小鼠的生长速度。Objective To investigate the effect of different light-dark cycles on the growth and activity of mice. Methods 180 ICR mice were divided into three groups. During four weeks the mice were exposed to one of three light-dark cycle regimes: light-dark cycles (LD )5/5, LD12/12 and LD 16/16. The locomotor activity was recorded continuously and analyzed by a computer. Growths of mice were measured every week. Results The biological rhythms of locomotor activity in those mice were synchronized with the relative light-dark cycles. The mice in LD12/12 group grew slower than those of other groups. Conclusion The light-dark cycles of different period can influence the activity cycle and growth of mice.

关 键 词：生长发育 生物节律 光暗循环 活动性 

分 类 号：R-332[医药卫生]