甲型血友病合并骨折围术期治疗探讨  

Perioperative Management of Fracture with Hemophilia A

作　　者：彭丹[1] 毛新展[1] 廖龙元[1] 倪江东[1] 

机构地区：[1]中南大学湘雅二医院骨科,湖南长沙410011

出　　处：《中国医师杂志》2005年第2期213-214,共2页Journal of Chinese Physician

摘　　要：目的　探讨甲型血友病合并骨折的围手术期治疗方法。方法　 7例合并骨折的甲型血友病患者 ,对所有患者实施术前、术中及凝血因子替代治疗、术后凝血因子检测 ,手术治疗骨折 ,随访平均 16个月。结果　本组 7例甲型血友病患者 ,亚临床型2例 ,轻型 2例 ,中型 2例 ,重型 1例 ,均获骨性愈合。术中、术后无血肿、感染、内固定松动及断裂等并发症发生。结论　经术前、术中和术后的充分准备治疗 ,合并血友病的骨折患者 ,可以通过手术治疗 ,获得良好骨愈合。Objective To study the perioperative treatment of the patients having fracture with hemophilia A. Methods Seven male hemophilia A patients with fractures were treated in our hospital from Jan. 1988 to Apr. 2003. All the patients received coagulation factor replacement treatment. The plasma level of factor Ⅷ was measured at preoperation, intraoperation and postoperation, fracture was treated by internal fixation, and the mean follow-up period was 16 months. Results In this series there were 1 severe, 2 moderate, 2 mild, and 2 pre-clinic hemophilia A patients, all patients had bone union during the follow-up, and no complications such as hematoma, infection and loosening or breaking of internal fixation happened. Conclusion The surgical treatment of fractures with hemophilia A can obtain excellent clinical outcome throug careful perioperative preparation.

关 键 词：甲型血友病 治疗 骨折 术中 术后 凝血因子 围术期 合并 结论 方法 

分 类 号：R687[医药卫生—骨科学]