RMI1和RMI2对卵巢肿瘤定性诊断价值比较  

Reliablility comparison of RMI1 and RMI2 in the qualitative diagnosis of ovarian tumors

作　　者：于兴江[1] 于琳[1] 冯仰伟[1] 

机构地区：[1]88医院妇产科,山东泰安271000

出　　处：《实用医药杂志》2005年第3期204-206,共3页Practical Journal of Medicine & Pharmacy

摘　　要：目的评估综合绝经后状态、超声评分、血清CA125的两种恶性危险度指数(Riskofmalignantindices,RMI)对卵巢肿瘤定性诊断的价值。方法对2000-01～2003-02在我院行妇科手术的卵巢肿瘤患者124例进行回顾性临床分析,应用RMI回归方程得出患者术前评分并以病理诊断为标准,计算RMI的灵敏度(Se)、特异度(Sp)、阳性预告值(PPV)、阴性预告值(NPV)并绘制出RMI1、RMI2、CA125的ROC曲线,采用SAS软件包处理临床数据。结果RMI1和RMI2对术前卵巢肿瘤定性诊断效果优于单一的血清CA125。当RMI在80～250水平时,RMI2比RMI1更好地反映了卵巢肿瘤的特性(P<0.0001)。RMI2为125水平时,Se为81%,Sp为90%,PPV为74%。ROC曲线表明:对卵巢肿瘤术前定性诊断效果从优到劣是RMI2、RMI1、CA125。结论RMI2对卵巢肿瘤术前定性诊断比RMI1有更高的可信度,是一种比较简单、可用于临床术前筛查卵巢肿瘤性质的新方法。Objective To evaluate the ability of two malignant risk indices(RMI1 and RMI2) incorporating menopausal status,serum CA125 level and ultrasound findings, which discriminate benign from a malignant ovarian tumors. Methods From January,2000 to February,2003, the data which were statistically managed by SAS software package were retrospectively analysised in 124 cases of ovarian tumors coming from inpatients and RMI scoring system was applied for obtaining the patient's pre-operative score based on pathologic diagnostic criterion.Results RMI(1 and 2) was superior to single serum CA125 level in discriminating the characteristic of ovarian tumors and for all cut off values between 80 and 250, RMI2 reflected the property of ovarian tumors better than RMI1 (P<0.0001), this result also be shown by receiver-operater characteristic curves . RMI2 at a cut off level of 125 gave a sensitivity of 81%, specificity of 90% and positive predictive value of 74%.Conclusions RMI2 is more reliable in discriminating the characteristics of ovarian tumors than RMI1, which can be used as a new method of screening the property of ovarian tumors in gynecologic clinics.

关 键 词：卵巢肿瘤 超声检查 诊断 

分 类 号：R737.32[医药卫生—肿瘤] R44[医药卫生—临床医学]