艾滋病痴呆综合征临床分析  

Clinical analysis of patients with AIDS dementia complex

作　　者：吴云成[1] 赵永波[1] 唐孟光[2] 谢雅英[1] 

机构地区：[1]上海交通大学附属第一人民医院神经内科,200080 [2]上海市传染病医院

出　　处：《中华神经科杂志》2005年第2期78-81,共4页Chinese Journal of Neurology

摘　　要：目的研究中国人群艾滋病(AIDS)痴呆综合征(ADC)的特征。方法对上海交通大学附属第一人民医院和上海市传染病医院收治的诊断为ADC的6例AIDS患者进行临床分析。结果所有患者均在清醒状态下表现为近记忆减退及注意力集中困难,其中3例伴有运动障碍。6例ADC患者中2例伴有空泡性脊髓病。诊断为AIDS后,ADC的平均诊断时间为6 5个月。所有患者均死于呼吸衰竭,平均寿命为41 8岁。结论ADC是AIDS患者最常见的神经系统并发症,常发生在AIDS的进展期。ADC通常伴有空泡性脊髓病,预后极差。Objective To investigate the clinical features of patients with AIDS dementia complex (ADC) in Chinese people. Methods Six patients with AIDS dementia complex in First People’s Hospital of Shanghai Jiaotong University and Shanghai Infectious Disease Hospital from 1999 to 2003 were analyzed. Results Short memory loss and poor concentration with preserved alertness occurred in all cases and motor disability was identified in three of them. Of the six ADC patients, there were two accompanied with vacuolar myelopathy. The mean time of ADC diagnosis was 6.5 months after the patients were identified with AIDS. All of the patients died of respiratory failure and the mean lifespan was 41.8 years. Conclusions ADC is the most common neurological complication of the AIDS patients and it might occurs in the advanced stage, and usually shown with vacuolar myelopathy and poor prognosis.

关 键 词：艾滋病痴呆综合征 临床分析 获得性免疫缺陷综合征 神经病学表现 

分 类 号：R749.2[医药卫生—神经病学与精神病学]