食管乳头状瘤研究分析  

Analysis of esophageal papilloma

作　　者：杜国莲[1] 唐学清[2] 朱本贵[1] 

机构地区：[1]泸州医学院附属医院消化科,四川泸州646000 [2]泸州医学院附属医院病理科,四川泸州646000

出　　处：《中国内镜杂志》2005年第2期116-118,共3页China Journal of Endoscopy

摘　　要：目的探讨食管乳头状瘤的内镜、临床病理特点.方法对25例食管乳头状瘤的胃镜、病理及临床资料进行回顾性总结分析.结果食管乳头状瘤好发于食管中下段,食管上1/3有1例(4%),中段11例(44%),下段13例(52%),食管中下段24例(96%);内镜下易误诊为食管息肉,11例内镜下治疗后随访6～36个月未见复发,3例并发其他部位肿瘤;病理学检查未见食管乳头状瘤恶变依据,仅有3例轻到中度异型增生;食管乳头状瘤临床表现无特异性,与反流性食管炎相似.结论黏膜的慢性炎症刺激等因素在食管乳头状瘤的发病中起一定作用;加强对食管乳头状瘤病人邻近脏器的检查和随访非常重要;食管乳头状瘤是否为癌前病变值得进一步研究.To explore the pathological, endoscopic and clinical characters and pathogenic mechanism of esophageal papilloma(EP). The anitrospective study of 25 cases of EP. Examined with upper gastrointestinal endoscopy, most the lesions were located at the middle or distal esophagus; the tumor of one of the cases was located at the upper 1/3rd of the esophagus (4%), 11 at the middle esophagus (44%), 13 at the distal part (52%), and 24 of the total 25 cases at the middle-distal esophagus (96%); may be mistaken as esophageal polyp under endoscopy; no recurrence was detected among the 11cases treated under endoscopy in the 6 months to 3 years′ follow-ups; synchronous or metachronous carcinoma in another site was found in 3 cases. No malignant evidence, only 3 cases showing light to medium dysplasia. Compared with reflux esophagitis, EP had no special symptom. [Conclusion] The chronic injury of mucus may play a role in the pathogenesis of EP; seeking the nearby cancer and follow-up are very important to the patients of EP; wether EP is a pre-cancer lesion worth further research.

关 键 词：食管乳头状瘤 胃镜检查术 病理学分型 微波治疗术 

分 类 号：R730.2[医药卫生—肿瘤]