XE-2100血液分析仪对异常细胞报警的评估  

Evaluation of morphologic abnormalities warnings of the system XE-2100 hematology analyzer

作　　者：束国防[1] 高茂馗[1] 芦慧霞[1] 

机构地区：[1]东南大学附属中大医院临床检验中心,江苏南京210009

出　　处：《东南大学学报（医学版）》2005年第2期98-100,共3页Journal of Southeast University(Medical Science Edition)

摘　　要：目的 :评估XE- 2 10 0血液分析仪对异常细胞报警的可信度。方法 :对XE -2 10 0血液分析仪测定提示有异常细胞报警和无异常细胞报警的标本各 2 0 0例进行手工涂片、瑞氏染色、显微镜油镜复检。结果 :以手工涂片、染色显微镜油镜复检为金标准 ,XE- 2 10 0血液分析仪对异常细胞报警的灵敏度为 99.3 4%,特异度为 80 .2 4%,阳性预测值为 75 .5 %,阴性预测值为99 .5 0 %。仪器法对未成熟粒细胞 (包括早幼粒、中幼粒和晚幼粒细胞 )检出的灵敏度为 95 .3 1%,特异度为 78.2 7%,阳性预测值为 45 .5 2 %,阴性预测值为 98.87%。仪器法对异常淋巴细胞检出的灵敏度为 63 .64 %,特异度为 96.47%,阳性预测值为 83 .5 8%,阴性预测值为 90 .3 9%。结论 :对XE 2 10 0血液分析仪显示异常细胞报警的标本都应该进行涂片、染色和显微镜复检。Objective To evaluate morphologic abnormalities warnings of the system XE-2100 hematology analyzer.Methods Manual stained differentiations were performed on 200 morphologic normal samples and 200 morphologic abnormal samples.Results The analyzer test showed the sensitivity to morphologic abnormalities was 99.34%,the specificity was 80.24%,the positive predictive value was 75.50% and the negative predictive value was 99.50%.The sensitivity to immature granulocytes was 95.31%,the specificity was 78.27%,the positive predictive value was 45.52% and the negative predictive value was 98.87%.The sensitivity to variant lymphocyte was 63.64%,the specificity was 96.47%,the positive predictive value was 83.58% and the negative predictive value was 90.39%.Conclusion The sample is warned by the system XE-2100 hematology analyzer must be manually differentiated.

关 键 词：异常细胞 血液分析仪 特异度 阴性 阳性 涂片 复检 结论 目的 显微镜 

分 类 号：R446[医药卫生—诊断学] R711[医药卫生—临床医学]