眼附属器横纹肌肉瘤的临床病理分析  

CLINICOPATHOLOGICAL ANALYSIS OF RHABDOMYOSARCOMA OF THE OCULAR ADENEXA

作　　者：冯官光[1] 易玉珍[1] 张洁[1] 李永平[1] 郑湖铃[1] 郑健梁[1] 林健贤[1] 刘金陵[2] 庞友鉴[2] 吴中耀[2] 

机构地区：[1]中山医科大学中山眼科中心眼科研究所 [2]中山医科大学中山眼科中心眼科医院

出　　处：《眼科学报》1994年第2期125-128,120,共5页Eye Science

摘　　要：12例原发于眼附属器的横纹肌肉瘤,男11例,女1例。最大年龄9岁,最小年龄3个月,平均4.6岁。12例均为单侧,其中眼眶9例,眼睑2例,球结膜1例。12例组织病理学分型:胚胎型8例,腺泡状型2例,多形性型2例。8例作免疫组化检查:肌红蛋白(Myoglobin)5例阳性,3例可疑阳性;结蛋白(Desmin)8例均阳性。免疫组化检验对诊断及鉴别诊断有重要意义。本组术后随访10例,除2例化疗1疗程后失访外,其余8例2例复发,3例在放疗及或化疗过程中病情不能控制而放弃治疗,2例放疗后半年因复发死亡,1例放疗后8个月健在。本组病例疗效差,除肿瘤恶性程度高外,起病年龄低,治疗不及时及治疗经验不足也是重要因素。本文尚讨论其临床病理诊断及鉴别诊断。12 cases including 11 males and 1 female of rhabdomyosarcoma of ocular adenexa were analysed. The average age of the patients was 4. 2 years. 9 cases of lesion were located in the orbit, 2 in the eyelid and 1 in conjunctiva. Pathologically 8 cases were embryonal forms, 2 alveolar, 2 polymorphic. Immunohistiochemical studies were performed in 8 cases, which showed desmin positive. Myoglobin presented strong or weak positive in 5 cases, suspicious positive in 3 cases. The clinical manifestation, prognosis and treatment were briefly discussed.

关 键 词：横纹肌肉瘤 病理学 眼肿瘤 

分 类 号：R739.720.2[医药卫生—肿瘤]