微量元素对Wistar乳鼠硒性白内障抑制作用的研究  

Study on Trace Elements Protecting against Selenite-induced Cataract in Suckling Wistar Rats

作　　者：曹军[1] 黄秀榕[1] 祁明信[1] 李楚芬[1] 吴克谦[1] 赵迅霞[1] 

机构地区：[1]宁夏医学院病理生理教研室,宁夏医学院眼科学教研室,宁夏医学院生理学教研室

出　　处：《眼科研究》1994年第2期81-84,共4页Chinese Ophthalmic Research

摘　　要：采用Ｗｉｓｔａｒ乳鼠经皮下注射亚硒酸钠诱发白内障，同时皮下注射汞、银、锂、钴等微量元素，动态观察白内障的发生与发展并测定晶体内有活性的超氧化物歧化酶（ＳｕｐｅｒｏｘｉｄｅｄｉｓｍｕｔａｓｅＳＯＤ）。结果表明：微量元素汞、银、锂、钴可不同程度地抑制和延级硒性白内障的发生与发展，晶体内有活性的ＳＯＤ含量与硒性白内障的发展有一定的相关性。sing suckling Wistar rats,selenite cataract was induced by selenite injection subcutaneously. Mean-while,the trace elements mercury,silver,lithum and cobalt were injected separately. The development of cataract was observed via slit lamp microscope dynamically and the concentrations of active superoxide dismu-tase(SOD)in lens were determined.The results demonstrated that trace elements Hg,Ag ,Li,and Co can protect against and delay the development of Se-cataract in different degrees and the concentrations of active SOD in lens are associated with the development of Se-cataract.

关 键 词：白内障 微量元素 硒 超氧物歧化酶 

分 类 号：R776.1[医药卫生—眼科]