An Efficient Cationic Cyclization Approach for the Construction of Labdane Diterpenoid Decalin Ring Skeleton  

作　　者：JinHuiYANG WeiDongZ.LI 

机构地区：[1]StateKeyLaboratoryofAppliedOrganicChemistry,LanzhouUniversity,Lanzhou730000

出　　处：《Chinese Chemical Letters》2005年第4期433-436,共4页中国化学快报（英文版）

基　　金：financial support from the National Outstanding Youth Fund(No.29925204)

摘　　要：An effective approach for the construction of the decalin ring skeleton of labdane diterpenoids was developed based on a key biomimetic cationic polyene cyclization of an epoxy allylsilane precursor. The synthetic approach demonstrated here would be useful in the enantioselective and diastereoselective total synthesis of natural labdane diterpenoids in general.An effective approach for the construction of the decalin ring skeleton of labdane diterpenoids was developed based on a key biomimetic cationic polyene cyclization of an epoxy allylsilane precursor. The synthetic approach demonstrated here would be useful in the enantioselective and diastereoselective total synthesis of natural labdane diterpenoids in general.

关 键 词：ALLYLSILANE labdane skeleton cationic cyclization biomimetic synthesis. 

分 类 号：O624[理学—有机化学]