^(13)C-尿素呼气试验对胃癌患者幽门螺杆菌感染的诊断价值  

Diagnostic value of ^(13)C-Urea breath test(^(13)C-UBT) in Helicobacter pylori infection of stomach cancer patients

作　　者：詹群珊 蔡筱彦 严建芬 黄勋 师瑞月 朱惠明 

机构地区：[1]广东省深圳市人民医院消化科,深圳518020

出　　处：《广西医学》2005年第3期339-340,共2页Guangxi Medical Journal

摘　　要：目的　探讨检测胃癌病人幽门螺杆菌感染的最佳方法。方法　对5 0例胃镜病理切片确诊为胃癌的患者,并1个月内未曾使用可能影响HP检测结果的药物者同步完成多聚酶链反应(PCR)、快速尿素酶试验(RUT)、13 C- UBT检测和病理。以PCR和病理(HE染色)阳性为诊断HP感染的标准。评价13 C UBT对HP感染的诊断价值。结果　13 C -UBT的敏感性10 0 % (34/34) ,特异性88% (14 /16 ) ,准确性96 % (48/5 0 ) ,阳性预测值94 % (34/36 ) ,阴性预测值10 0 % (14 /14 )。结论　13 C -UBT可作为HP与胃癌相关性研究的最可靠的方法。Objective To explore the best methods to examine HP infection of stomach cancer patients.Methods 50 cases who have been diagnosed as stomach cancer by pathology slice.All of them who have never taken drugs which will probably affect the reliability in detection of HP infection in a recent month underwent polymerase chain reaction(PCR),rapid urease test(RUT), 13C-Ure breath test( 13C-UBT) and histology examination.Both histology(HE staing) and PCR positive was considered as the standard for diagnosis of HP infection.The diagnostic value of 13C-UBT in HP infection was cvaluated.Results Contrast the consequence,the sensitivity,specificity,accuracy,negative predictive value and positive predictive value of 13C-UBT were 100%(34/34),88%(14/16),96%(48/50),100%(14/14),94%(34/36).Conclusion The 13C-UBT can be considered as the most reliable way to study HP and stomach caner.

关 键 词：^13C-尿素呼气试验 幽门螺杆菌 胃癌 

分 类 号：R735.2[医药卫生—肿瘤]