^（59）Fe在大鼠铁代谢研究中的应用  

THE APPLICATION OF ISOTOPE 59Fe ON IRON METABOLISM IN DIFFERENT IRON NUTRITIONAL STATUS OF RATS

作　　者：刘戌年 Vite.,FE 

机构地区：[1]新疆昌吉州人民医院

出　　处：《营养学报》1994年第4期382-385,共4页Acta Nutrimenta Sinica

基　　金：美国加利福尼亚大学科研基金

摘　　要：６０只雄性ＳＤ断奶大鼠，分为铁正常、铁缺乏和铁缺乏补充铁１０倍于常量三组。采用５９Ｆｅ示踪法测量大鼠全身５９Ｆｅ储留量和各器官、组织的分布。结果显示，铁正常组大鼠全身铁储留率为３１．０％～３６．０％，铁缺乏组大鼠为８４．１％～９３．３％，铁缺乏大鼠补铁后储留率由２１．８％急剧下降至６．８％。铁缺乏组大鼠小肠粘膜、肝脏、血液与骨骼等铁吸收储留器官、组织铁的分布显著高于铁正常组大鼠，铁缺乏大鼠补铁后组织器官的分布最低。而小肠灌洗液、结肠和粪便内铁分布表现出完全相反的结果．ixty male weanling Sprague Dawley rats were made iron normal,irondeficient and iron supplementation models by feeding the diet with normaldose iron,without iron and 10 times normal dose iron, Radioactivity inwholebody and various organs or tissues were measured using radio isotope59Fe with Whole Body Counter and Y-Scintillation Counter.The results showed that the rate of iron retention of wholc body in ironnormal rats were 31.0%-33.1%, iron deficient rats were 89.2%-93.3%,and it was reduced from 21.8%to 6.8%by iron supplemenation, The irondistribution in the intestinal mucosa,liver, blood and carcass of iron defi-cient rats were significantly higher than the iron normal rats, and irondistribution in those organs in iron supplemented rats were lowest.

关 键 词：铁营养 铁59 铁代谢 

分 类 号：R151.2[医药卫生—营养与食品卫生学]