端粒酶与年龄相关性白内障的关系  

Relationship between telomerase and age-related cataract

作　　者：张楠[1] 郑广瑛[1] 

机构地区：[1]郑州大学第一附属医院眼科,河南省郑州市450052

出　　处：《眼科新进展》2005年第2期184-186,共3页Recent Advances in Ophthalmology

摘　　要：作为维持染色体末端端粒长度的端粒酶( telom-erase)与细胞的永生化及恶性变有密切关系,关于它在眼科领域的研究目前正处于起步阶段。本文就端粒酶在晶状体上皮细胞生长分化及年龄相关性白内障发病机制、病理生理过程中可能的作用进行综述。As a specialized reverse transcriptase responsible for maintaining the end of chromosomes,telomerase is closely related to cellular immortalization and cancer development.The research about it in ophthalmic field just reaches a basic stage.Here we reviewed the effect of telomerase in proliferation of lens epithelial cells and pathologic mechanism of age-related cataract.

关 键 词：端粒酶 端粒 晶状体上皮细胞 白内障 

分 类 号：R776.1[医药卫生—眼科]