儿童耳鼻咽喉原发恶性肿瘤(附70例)  

The clinical analysis of malignant tumors of otorhinolaryngologic region in children

作　　者：任晓勇[1] 张向红[1] 王建刚[1] 康安静[2] 

机构地区：[1]西安交通大学第二医院耳鼻喉科,陕西西安710064 [2]西安交通大学第二医院病理科,陕西西安710004

出　　处：《现代肿瘤医学》2005年第2期250-253,共4页Journal of Modern Oncology

摘　　要：目的探讨儿童耳鼻咽喉原发恶性肿瘤的特点,提高临床诊治水平.方法回顾分析1965～1999年间我院收治的70例14岁以下儿童耳鼻咽喉原发恶性肿瘤的临床资料.结果非上皮源性恶性肿瘤56例,占总数的80%,包括横纹肌肉瘤19例,纤维肉瘤8例,软骨肉瘤4例,黑色素瘤12例,嗅神经母细胞瘤4例,恶性淋巴瘤9例;上皮来源肿瘤14例,占总数的20%,包括未分化癌9例,乳头状癌5例;治疗采用手术切除+放疗和/或化疗37例,单纯手术切除4例,非手术治疗(放疗和/或化疗)20例,放弃治疗9例.获随访资料61例,存活3年以上者11例,均为接受手术切除+放疗或化疗者,3年生存率为18.03%.结论儿童耳鼻咽喉原发恶性肿瘤恶性度高,预后差,尽早确诊并采用综合治疗可望取得较好疗效.Objective To explore the clinical characte ri stics of malignant tumors of otorhinolaryngologic region in children and to impr ove the level of diagnosis and therapy. Methodes A total 70 cases of malignant tumors of otorhinolaryngologic region in children between 1965 and 1999 were analyzed retrospectively.Results Of t he cancers,nonepithelail malignant tumor accounted 80%,epithelail malignant tum or 20%.Treatment included surgery, irradiation or/and chemotherapy and surgery plus irradiation or chemotherapy . Sixty one cases were followed up,11 cases sur vived over 3 years,and they all accept the treatment of surgery plus irradiation or chemotherapy.The survival rate of 3 years was 18.03%.Conclusion Malignant tumors of otorhinolaryngologic region have aggressive behav ior and poor prognosis. The keys of efficient treatment and preventing from recu rrence are earlier diagnosis and selecting comprehensive therapy.

关 键 词：儿童 耳鼻咽喉 肿瘤 诊断 治疗 预后 

分 类 号：R739.6[医药卫生—肿瘤]