Postnatal Developmental Expression of Calbindin,Calretinin and Parvalbumin in Mouse Main Olfactory Bulb  

作　　者：Zhao-PingQIN Shu-MingYE Ji-ZengDU Gong-YuSHEN 

机构地区：[1]DepartmentofBiology,CollegeofLifeScience,ZhejiangUniversity,Hangzhou310027,China

出　　处：《Acta Biochimica et Biophysica Sinica》2005年第4期276-282,共7页生物化学与生物物理学报（英文版）

基　　金：This work was supported by a grant from the National Natural Science Foundation of China (30070190)

摘　　要：The distribution of calbindin,calretinin and parvalbumin during the development of the mouse main olfactory bulb (MOB) was studied using immunohistochemistry techniques.The results are as follows: (1)calbindin-immunoreactive profiles were mainly located in the glomerular layer,and few large calbindin- immunoreactive cells were found in the subependymal layer of postnatal day 10 (P10) to postnatal day 40 (P40) mice;(2) no calbindin was detected in the mitral cell layer at any stage;(3) calretinin-immunoreactive profiles were present in all layers of the main olfactory bulb at all stages,especially in the olfactory nerve layer,glomerular layer and granule cell layer;(4)parvalbumin-immunoreactive profiles were mainly located in the external plexiform layer (except for P10 mice);(5)weakly stained parvalbumin-immunoreactive pro- files were present in the glomerular layer at all stages;and (6) no parvalbumin was detected in the mitral cell layer at any stage.The distribution of calbindin,calretinin and parvalbumin during the development of the mouse main olfactory bulb (MOB) was studied using immunohistochemistry techniques.The results are as follows: (1)calbindin-immunoreactive profiles were mainly located in the glomerular layer,and few large calbindin- immunoreactive cells were found in the subependymal layer of postnatal day 10 (P10) to postnatal day 40 (P40) mice;(2) no calbindin was detected in the mitral cell layer at any stage;(3) calretinin-immunoreactive profiles were present in all layers of the main olfactory bulb at all stages,especially in the olfactory nerve layer,glomerular layer and granule cell layer;(4)parvalbumin-immunoreactive profiles were mainly located in the external plexiform layer (except for P10 mice);(5)weakly stained parvalbumin-immunoreactive pro- files were present in the glomerular layer at all stages;and (6) no parvalbumin was detected in the mitral cell layer at any stage.

关 键 词：CALBINDIN CALRETININ PARVALBUMIN MOUSE main olfactory bulb 

分 类 号：Q593[生物学—生物化学] Q434