经皮肝脏射频消融术对肝癌治疗的初步研究  

Radiofrequency ablation in treatment of malignant liver tumors

作　　者：封云[1] 佟小强[1] 杨敏[1] 邹强[1] 吕永兴[1] 邹英华[1] 

机构地区：[1]北京大学第一医院放射科,北京100034

出　　处：《中国介入影像与治疗学》2005年第2期89-92,共4页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的研究射频消融对肝脏恶性肿瘤的治疗效果.方法对16例肝脏恶性肿瘤患者共18个病灶超声引导下进行射频消融治疗,大小1.9～6.6 cm.术前术后均进行增强CT扫描,并定期随访.结果术后病灶完全坏死率为68.7%,复发率为36.6%.完全坏死率的相关因素分析显示病灶直径、介入治疗史、消融温度、电极针大小为相关因素.结论射频消融是原发性及转移性肝癌安全有效的方法,其长期效果尚待进一步观察.Objective To investigate the efficacy and safety of radiofrequency ablation in treating malignant liver tumors. Methods Sixteen patients with total 18 malignant liver tumors including 11 HCC and 7 metastatic tumors were treated with US-guided radiofrequency ablation, 6 were small tumors (≤3 cm) and 12 of large ones(>3 cm). Preoperative and post-procedural CT scans were taken in all 16 patients. During follow-up patients underwent enhanced CT in every 2-3 month interval. Results Complete necrosis was obtained in 11 tumors of 18 (68.7%) including 5 small tumors (83.3%) and 6 large ones (50%). Local and intrahepatic recurrences were found in 4 complete necrosis lesions during a mean follow-up of 8.5 months (2-10 month). Tumor's diameter, patients with TAC or TACE history, ablation temperature and size of electrodes showed correlation with necrosis. Conclusion Radiofrequency ablation is effective and reliable in treating malignant liver tumors, and the long-term results are still under investigation.

关 键 词：射频消融术 肝癌治疗 步研究 经皮 肝脏恶性肿瘤 射频消融治疗 恶性肿瘤患者 增强CT扫描 相关因素分析 超声引导下 转移性肝癌 治疗效果 术前术后 定期随访 消融温度 长期效果 坏死率 病灶 复发率 治疗史 电极针 原发性 

分 类 号：R735.7[医药卫生—肿瘤]