奥扎格雷钠治疗进展型脑梗死的疗效观察  

Clinical observations on the therapeutic effect of sodium ozagrel in treatment of progressive ischemic stroke

作　　者：于旭[1] 徐忠信[1] 畅美季[2] 张朝民[2] 

机构地区：[1]吉林大学中日联谊医院神经内科,吉林长春130021 [2]长春市中心医院神经内科,吉林长春130061

出　　处：《吉林医学》2005年第4期376-377,共2页Jilin Medical Journal

摘　　要：目的:评价奥扎格雷钠对进展型脑梗死的临床疗效。方法:应用奥扎格雷钠治疗进展型脑梗死,并与葛根素治疗对照。观察两组患者治疗前后的临床疗效及血液流变学变化。结果:奥扎格雷钠治疗组用药前后神经功能缺损评分比对照组明显降低(P<0.05),治疗后14d奥扎格雷钠治疗总有效率、明显有效率(分别为87.5%和70%),明显高于对照组(分别为47.5和32.5%)两组比较差异有显著意义(P<0.05)。血液流变学各项指标也有显著性意义(P<0.05)。结论:奥扎格雷钠是治疗进展型脑梗死的有效药物。Objective To evaluate the therapeutic effect of sodium ozagrel in treatment of progressive ischemic stroke. Method Patients with progressive stroke were treated with ozagrel in the trial group,while in the control group with puerarin. We judged the clinical nervous function and defect degree before and after 14d treatment according to the nervous defect standard(NDS)and the changes of hemorrheology. Results There was a significant difference in general effective rate and significantly effective rate between the trial group and the control group (P<0.05),and in all laboratory indexes there was also an apparent effects. Conclusion The therapeutic effects of ozagrel is satisfactory and safe.

关 键 词：奥扎格雷钠 进展型脑梗死 临床疗效 

分 类 号：R743[医药卫生—神经病学与精神病学]