调强放疗的计划设计  

Treatment Planning for Intensity-Modulated Radiation Therapy

作　　者：戴建荣[1] 胡逸民[1] 

机构地区：[1]中国医学科学院协和医科大学肿瘤医院,北京100021

出　　处：《中国医疗器械信息》2005年第2期9-12,共4页China Medical Device Information

摘　　要：本文系统介绍调强放疗(IMRT)的计划设计方法。与常规/适形放疗计划相同,IMRT计划设计过程也包含6个步骤,分别是输入患者一般信息和图像信息,登记和配准图像,定义解剖结构和给定临床处方剂量要求,采用正向或逆向方式确定射野参数,评价治疗计划,输出治疗计划报告和传输射野数据。与常规/适形放疗计划不同,IMRT计划设计有3个鲜明的特点,分别是只能采用逆向方式设计,需要定义剂量成形结构,选择射野方向的原则不同。IMRT计划设计方法还在迅速发展中,主要的发展趋势有确定照射子野序列的方法由两步法向一步法过渡,优化参数的数目不断增加和参数之间逻辑关系变得复杂,优化的目标函数和约束条件越来越体现临床要求。Here we systematically introduce the treatment planning techniques for intensity-modulated radiation therapy (IMRT). Similar toconventional 2D/3D radiotherapy planning, IMRT planning procedure has six steps: enter patient demographic information and imagedate; register and match (fuse) images; define anatomical structures and prescribe doses; determine beam parameters through forwardplanning or inverse planning; evaluate treatment plans; print a report and transfer beam data for the final plan. Different from conventional2D/3D planning, IMRT planning has three unique features: beam parameters can be determined through inverse planning; it is necessaryto define dose shaping structures; the rules for choosing beam directions have changed. IMRT treatment planning techniques are still underrapid development. The main developing directions are: Two-step strategy is being replaced by one-step strategy for generating leafdelivery sequences; The number of optimization parameters is increasing and the relationship between parameters is becoming morecomplex; the objectives and constraints of optimization problem are more and more reflecting clinical requirements.

关 键 词：计划设计 调强放疗 IMRT 设计方法 放疗计划 治疗计划 系统介绍 图像信息 处方剂量 解剖结构 射野方向 逻辑关系 优化参数 临床要求 约束条件 目标函数 一步法 两步法 适形 逆向 

分 类 号：R730.55[医药卫生—肿瘤] R730.264[医药卫生—临床医学]