实验性甲状腺肿甲状腺过氧化物酶活性的改变  

Changes of Thyroid peroxidase activity in the experimental animals with Goiter

作　　者：苏天水[1] 欧阳安[1] 秦贵军 于博 张玉凤[1] 王建波 

机构地区：[1]河南省医学科学研究所内分泌研究室

出　　处：《中国地方病学杂志》1994年第2期86-88,126,共4页Chinese Jouranl of Endemiology

摘　　要：分别测定低碘，致甲肿物质（ＭＭＩ）和高碘三种原因引起甲状腺肿动物的甲状腺过氧化物酶ＴＰＯ活性。结果显示低碘组和ＭＭＩ组ＴＰＯ活住显著高于对照组；高碘组ＴＰＯ活性明显降低．加喂高酪蛋白的实验组，低碘组和ＭＭＩ组Ｔｔｏ活性显著下降；而高碘组ＴＰＯ活性明显升高．结果提示高酪蛋白对甲状腺肿动物的ＴＰＯ活性有影响．The thyroid peroxidase (TPO) activitis in the experimental animals with gotter caused by iodine deficiency (A),goitrogenic agents (B) and excess iodine (H) were determinated respectively. The results indicate that the TPO in both groups (A) and (B) were increased significantly,the group (H) was reduced markedly. The TPO in (A) and (B) reduced markedly but increased significantly in group (H) after administration of casein. These suggest that high casein diet may affect on. TPO activity of the thyroid tissue in the experimental animals with gotter.

关 键 词：甲状腺肿 碘 酪蛋白 过氧化物酶 

分 类 号：R581.303[医药卫生—内分泌]