An Efficient Way for Glycosylation of Spirostanol  

作　　者：ShuJieHOU ChuanChunZOU PingShengLEI DeQuanYU 

机构地区：[1]InstituteofMateriaMedica,PekingUnionMedicalCollege＆ChineseAcademyofMedicalSciences,Beijing100050

出　　处：《Chinese Chemical Letters》2005年第5期593-596,共4页中国化学快报（英文版）

基　　金：Financial support of this research from the National Natural Science Foundaion of China(20372085)is gratefully acknowledged by the authors.

摘　　要：Using thioglycosides as donors, trimethylsilyl trifluoromethanesulfonate (TMSOTf) and N-iodosuccinimide(NIS) as promoter, a modified procedure for the glycosylation of spirostanol was developed. A series of saponins were synthesized in mild condition with excellent yields.

关 键 词：Spirostanol glycoside GLYCOSYLATION trimethylsilyl trifluoromethanesulfonate ethyl  1-thioglycoside N-iodosuccinimide. 

分 类 号：O629.1[理学—有机化学]