长江水质对SHE细胞的恶性转化作用  

Transformation of Water Samples in Changjiang River With Syrian Hamster Embryo Cells

作　　者：丁文兴[1] 聂岚[1] 朱惠刚[1] 

机构地区：[1]上海医科大学环境卫生教研室

出　　处：《中国公共卫生学报》1994年第6期332-334,共3页

摘　　要：应用ＳＨＥ细胞对长江中下游５城市的源水及自来水进行细胞毒性及转化试验。结果表明，长江中下游的源水及自来水均可导致细胞的转化，且有较好的剂量－反应关系。转化灶特征表明所有转化灶细胞均失去了接触抑制的特点。Using Primary Syrian Hamster Embryo(SHE)cells to detect the cell toxicity the ability of transformation of water samples in varied five cities in Changjiang River. The results showed both the source water and rumming water could cause cell malignant transformation,and the results had a doserelated response. The characteristic of tile foci indicated that thetransformed cells lose comtact inhibition.

关 键 词：污染物 水质 细胞转化 胚细胞 致癌物 环境污染 

分 类 号：R730.231[医药卫生—肿瘤] X520.31[医药卫生—临床医学]