杜仲提取物对亚硝化反应的抑制作用  

Study on Inhibition on Nitrosation of Extraction from Eucommia Ulmoides

作　　者：吴春[1] 张立惠[2] 孔琪[1] 朱双鹏[1] 

机构地区：[1]哈尔滨商业大学化学中心,哈尔滨150076 [2]哈尔滨商业大学学报编辑部

出　　处：《化学与粘合》2005年第3期183-185,共3页Chemistry and Adhesion

基　　金：黑龙江省自然科学基金 :0 90 3 ;哈尔滨市青年科学基金 2 0 0 4AFQXJ0 3 4。

摘　　要：采用正交试验法从杜仲中提取活性物质,研究其对亚硝化反应的抑制作用。用紫外光解法测定了杜仲提取物对N-二甲亚硝胺(NDMA)体外合成的阻断作用及对亚硝酸钠的清除作用。结果表明:从杜仲中提取抗亚硝化反应活性物质的最佳条件是:料液比为1∶8,在80℃下用70%的乙醇回流提取1 5h。该活性提取物对亚硝胺合成的最大阻断率为78 57%,对亚硝酸钠的最大清除率为73 94%。The optimum conditions for extraction from Euconmmia ulmoides and its inhibition on nitrosation were studied.The results showed that the optimum extraction conditions were as follows:concentration of alcohol solution was 70%,the ratio of solid to solution was 1∶8,extraction was carried out at 80℃ for 1.5 hour.The maximum capabilities of inhibiting formation of nitrosamine and scavenging rate of sodium nitrite were 78.57% and 73.94% respectively.

关 键 词：亚硝化反应 抑制作用 提取物 杜仲 活性物质 亚硝酸钠 正交试验法 清除作用 阻断作用 体外合成 最佳条件 回流提取 亚硝胺 光解法 料液比 阻断率 清除率 

分 类 号：O613.61[理学—无机化学] TS202.3[理学—化学]