持续腰大池引流在颅内动脉瘤术后的临床应用价值  

Clinical Study of Continuous Lumbar Drainage of Cerebrospinal Fluid in Treatment of Brain Aneurysm

作　　者：宋仁兴[1] 赵奇煌[1] 杨新乾[1] 吴卫[1] 

机构地区：[1]首都医科大学附属北京朝阳医院神经外科,北京100020

出　　处：《中国医药导刊》2005年第2期82-84,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨持续腰大池引流在颅内动脉瘤术后的临床应用价值。方法:颅内动脉瘤术后,治疗组72例行持续腰大池 引流,对照组49例每天腰椎穿刺,通过比较两组并发症及预后评定疗效。结果:经过持续腰大池引流后,有症状性脑血管痉 挛的发生率从34.69％降低为18.31％,脑积水的发生率从26.53％降低为11.27％,脑梗塞的发生率从20.4％降低为 7.04％.出院时恢复良好者占76.06％,而对照组为57.14％,以上均有统计学意义(P<0.05),治疗组并发症的发生率为 5.63％,死亡率为零,对照组并发症的发生率为零,两组之间并发症的发生无统计学意义。结论:持续腰大池引流能够减少 蛛网膜下腔中的痉挛因素,减轻脑血管痉挛的发生,减少并发症,改善预后。Objective: The goal of the study was to investigate the value of continuous lumbar drainage of cerebrospinal fluid in treatment of brai n aneurysm. Methods: The treatment group consisted of 72 patientsin whom a continuous lumbar drainage of cerebrospinal fluid had been placed, whereas the control group composed of 49 patients who received daily lumbar drainage. The complication and outcome were measured. Results: The presence of continuous lumbar drainage of cerebrospinal fluid conferred a statistically significant protective and beneficial effect,it reduced the incidence of clinical vasospasm from 34.69% to 18.31% ,the occurrence of hydrocephalus from 26.53% to 11. 27% , the occurrence of infarction from 20.4% to 7.04% , and the occurrence of good recovery from 76.16% to 57.14%. The complications between the two groups were no statistically significant(P < 0.05). Conclusion: Continuous lumbar drainage of cerebrospinal fluid in treatment of brain aneurysm reduced the risk of clinically evident vasospasm and its sequelae,improved outcome.

关 键 词：持续腰大池引流 颅内动脉瘤 术后 临床应用 

分 类 号：R739.4[医药卫生—肿瘤]