畜禽疫苗佐剂研究进展  

Recent Progress in Veterinary Vaccine Adjuvant

作　　者：张玲华[1] 郭勇[1] 田兴山[2] 潘木水[2] 黄小光[2] 周风珍[2] 邝哲师[2] 李国立[2] 孙晓刚[2] 陈薇[2] 

机构地区：[1]华南理工大学生物工程学院,广东广州510641 [2]广东省农业科学院农业生物技术研究所,广东广州510640

出　　处：《生物技术通讯》2005年第2期231-233,共3页Letters in Biotechnology

基　　金：广州市科技攻关重点项目(2003Z2-E0221);广东省农业攻关项目(2003B21403)

摘　　要：畜禽用疫苗主要是亚单位疫苗、减毒或灭活细菌/病毒疫苗,为了使疫苗对动物能达到长效持久的保护,必须使用有效的佐剂。根据不同的作用方式,目前可将佐剂主要分为2大类:疫苗传递系统的佐剂、免疫刺激作用佐剂。本文探讨了近年来畜禽用疫苗佐剂的功能及其发展趋势,概述了其应用研究的进展。The veterinary vaccine mainly comprise of either subunit, live attenuated or inactivater bacteria/viruses. These vaccines would require optimal adjuvants and delivery systems to accord long-term protection from infectious diseases in animals. Adjuvants can be broadly divided into two classes, based on their principal mechanisms of action:vaccine delivery systems and immunostimulatory adjuvants. The function and development of adjuvant in animals were dicussed here, and the recent progress in application was also included.

关 键 词：畜禽疫苗佐剂 免疫刺激剂 疫苗传递系统 乳化 功能 发展趋势 

分 类 号：S859.797[农业科学—临床兽医学]