机构地区:[1]长治医学院人体解剖学教研室,山西省长治市046000
出 处:《中国临床康复》2005年第14期250-251,共2页Chinese Journal of Clinical Rehabilitation
摘 要:背景:颈椎病手术治疗时,常用颈椎前外侧途径,主要显露颈椎椎体、椎间盘、钩椎关节等部位。近年来这方面的报道多为对其局部性的研究,特别是对颈椎与对应的血管神经距离数据的观测研究较少。目的:观测颈部血管与神经的关系及其与颈椎的距离,为颈椎病手术治疗中预防医源性血管和神经损伤提供帮助。设计:以解剖学标本为实验对象,单一样本研究。单位:一所医学院解剖教研室。对象:2003-07/2004-05在长治医学院解剖教研室完成,成人防腐标本20具40侧(由长治医学院解剖教研室提供),男36侧,女4侧。方法:观测了40侧成人标本颈部血管与神经的伴行关系,颈部血管的长度及起止点与相邻颈椎间的距离。主要观察指标:①相关动脉与神经的伴行关系。②相关动脉的长度及其起止点与相邻颈椎的距离。结果:20具标本40侧均进入结果分析。面动脉与舌神经伴行,起点距相邻椎体C3为(18.5±7.2)mm。舌动脉与舌下神经伴行,起点距相邻椎体C2~3为(19.7±8.4)mm。甲状腺上动脉与喉上神经外支伴行,起点距相邻椎体C3为(17.0±5.7)mm,止点距相邻椎体C5为(18.2±2.5)mm。喉上动脉与喉上神经内支伴行,起点距相邻椎体C3为(15.7±6.7)mm,止点距相邻椎体C3为(19.7±5.8)mm。甲状腺下动脉起点距相邻椎体C7为(17.3±5.5)mm,止点距相邻椎体C7为(11.BACKGROUND:Chemotherapy has been the very important adjunctive treatment for t he patients with large intestine cancer. However,obvious individual difference e xists in the sensitivity of the patients to the chemotherapeutic drugs,and the d ifference is related with the age and sex of the patients or not? OBJECTIVE:To make an exploratory discussion of that whether the difference of the sensitivity of chemotherapeutic drugs exists in different ages and different sexes of the patients with epidemiological investigation of the tumor cell surv ival rate. DESIGN:Controlled experimental study based on pathological samples. SETTING:General surgery department of an affiliated hospital of a medical coll ege. PARTICIPANTS:Tumor cell samples of 169 cases of colorectal cancer tissue obtai ned from patients with colorectal cancer at the Department of General Surgery of the affiliated hospital of North Sichuan Medical College during the period from January 2001 to January 2003 were involved as subjects.The patients,97 males an d 72 females,were made a definite diagnosis of the large intestine cancer by ope ration and pathological examination and have not been treated with chemotherapy before operation. METHODS:The sensitivity of chemotherapy drugs were measured on the survival tu mor specimens of 169 patients with colorectal carcinoma with Methyl thiazolyl te trazolium(MTT) test method in vitro.The differences of different ages and differ ent sexes were analyzed in patients. MAIN OUTCOME MEASURES:The absorbance values of tumor cell 72 hours after treat ment with chemotherapeutic drugs. RESULTS:There was no obvious significance of the tumor's sensitivity to chemot herapeutic agents in different ages and sexes in patients with colorectal cancer (P >0.05). CONCLUSION:The individual difference of sensitivity for chemotherapeutic agent s in patients with colorectal cancer is not related with the age and gender , ne edless to consider age and gender in selecting chemotherapeutic agents for diffe rent individuls.
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