卵巢恶性生殖细胞肿瘤手术方式的探讨  

Study of Different Surgeries in Malignant Ovarian Germ Cell Neoplasms

作　　者：黄永文[1] 李孟达[1] 刘富元[1] 李玉洁[1] 李艳芳[1] 

机构地区：[1]中山大学肿瘤防治中心,510060

出　　处：《实用癌症杂志》2005年第1期75-77,共3页The Practical Journal of Cancer

摘　　要：目的　本文分析164例卵巢恶性生殖细胞肿瘤的手术疗效,探讨治疗该瘤更合理的手术方式。方法　回顾性分析164例卵巢恶性生殖细胞肿瘤患者的临床资料,其中5 7例采用保留生育功能的术式;10 7例采用不保留生育功能的传统术式。2组均根据个体状况辅以适当的化疗(和/或放疗)。结果　保留生育功能组和不保留生育功能组的5年生存率分别为69.0 1% (3 9/5 7)、5 4.94% (5 9/10 7) (P >0 .0 5 )。2组术后并发症发生率分别为3 .5 1% (2 /5 7)、3 .74% (4 /10 7) (P >0 .0 5 )。多因素分析显示临床分期、病理类型、残留肿瘤体积是影响预后的主要因素(P均<0 .0 5 )。结论　卵巢恶性生殖细胞肿瘤患者可根据需要采用保留生育功能的术式,并辅以适当的化疗和(或)放疗。Objective This study was conducted to compare the outcomes in patients with malignant ovarian germ cell cancer who were treated with different surgeries and seek suitable treatments for such patients.Methods Clinical data of women with malignant ovarian germ cell neoplasms were analyzed retrospectively.Fifty-seven cases undergoing fertility saving surgery received appropriate adjuvant chemotherapy and/or radiotherapy.One hundred and seven cases undergoing non-conservative surgery received appropriate adjuvant chemotherapy and/or radiotherapy.Results 5-year survival rates in these two group were 69.01%(39/57) and 54.94%(59/107)(P>0.05),respectively.The incidence of operation-related complications in such ones were 3.51%(2/57) and 3.74%(4/107)(P>0.05),respectively.Clinical stage,histological type and the volume of residue were the mainly prognostic factors in multianalysis(P<0.05).Conclusion Women with malignant ovarian germ cell neoplasms could receive fertility saving operation if necessary and should receive adjuvant chemotherapy and/or radiotherapy.

关 键 词：卵巢恶性生殖细胞肿瘤 手术方式 保留生育功能 并发症发生率 肿瘤患者 回顾性分析 5年生存率 多因素分析 手术疗效 临床资料 传统术式 临床分期 病理类型 肿瘤体积 功能组 放疗 化疗 

分 类 号：R737.31[医药卫生—肿瘤] R737.305[医药卫生—临床医学]