椎间盘移植实验──生物力学研究  

Intervertebral disc autografting(Biomechanical study)

作　　者：阮狄克[1] 陆瓞骥[1] 周鸿奇[1] 沈根标[1] 孙宏慧[1] 罗卓荆[1] 梁智仁[1] 

机构地区：[1]第四军医大学唐都医院骨科,香港大学骨科学系

出　　处：《中国脊柱脊髓杂志》1994年第1期16-20,共5页Chinese Journal of Spine and Spinal Cord

摘　　要：本实验在６只猴体上制备自体椎间盘移植模型，观察术后不同时期生理载荷下屈伸活动时移植椎间盘的刚度（ｓｔｉｆｆｎｅｓｓ）变化。结果表明：术后２月，移植的Ｌ３～４椎间盘在整个屈伸活动中较上、下正常对照椎间盘的变形增大；术后４月，移植椎间盘变形接近正常对照椎间盘；术后６月，移植椎间盘刚度明显恢复。实验结果提示术后早期有腰椎节段性不稳倾向，中晚期稳定性恢复，移植椎间盘可满足生理活动功能需要。Six rhesus were devided into 3 groups.The L3￣4 intervertebral disc was completely mobilized and was then anchored with sutures. The specimens from L1 to sacrum were harvested after 2, 4 and 6 months respectively. The stiffness of intervertebral disc autogafting was measured with a motion analysis system (Elite) while the spinal specimen was being loaded into flexion and extension. It showed that the deformation of L3￣4 disc increased in 2 months group. Finally, the stiffness was reconstituted and the deformation recovered in 6 months group. The present results showed that intervertebral disc autografting can function well under physiologic loading in flexion and extension,(Department of Orthopedic Surgery, Tangdu Hospital,The 4th Military Medical University,Xi'an,Shanxi,710038)

关 键 词：猴子 椎间盘移植 刚度 变形 

分 类 号：R687[医药卫生—骨科学]