纳米级固定化猪胰脂肪酶催化三亚甲基碳酸酯的开环聚合研究  

Ring-opening Polymerization of Trimethylene Carbonate Catalyzed by PPL Immobilized on Silica Nanoparticles

作　　者：喻湘华[1] 卓仁禧[1] 冯俊[1] 

机构地区：[1]武汉大学化学系,生物医用高分子材料教育部重点实验室,武汉430072

出　　处：《高等学校化学学报》2005年第5期978-981,F010,共5页Chemical Journal of Chinese Universities

基　　金：国家重点基础发展规划项目(批准号:G1999064703);国家自然科学基金(批准号:29934060)资助.

摘　　要：以纳米级固定化猪胰脂肪酶(IMPPL)催化三亚甲基碳酸酯(TMC)的开环聚合,研究了IMPPL浓度、聚合反应温度和聚合反应时间对聚三亚甲基碳酸酯(PTMC)分子量和产率的影响.同时也研究了回收再利用的IMPPL对TMC开环聚合的催化作用以及IMPPL对PTMC的降解作用.实验结果表明,IMPPL不仅在60～100℃能有效地催化TMC的开环聚合,而且在较高的温度下IMPPL可以有效地催化PTMC的降解.回收使用的固定化酶可表现较高的催化活性及重复利用性.The ring-opening polymerization of trimethylene carbonate(TMC) catalyzed by the immobilized porcine pancreas lipase on silica nanoparticles(IMPPL) was explored. The influences of IMPPL concentration and reaction temperature as well as reaction time on the molecular weight and yield of PTMC were studied. The ring-opening polymerization of TMC using the recycling IMPPL and the degradation of PTMC in the presence of IMPPL were also investigated. The experimental data showed that this IMPPL could not only catalyze the ring-opening polymerization of TMC at 60—100 ℃ efficiently, but also catalyze the degradation of PTMC at relatively high temperatures. The recycling IMPPL showed better catalytic activity and could be used repeatedly.

关 键 词：聚碳酸酯 开环聚合 猪胰脂肪酶 固定化酶 纳米粒子 

分 类 号：O633[理学—高分子化学]