Synthesis, Structure and Biological Activities of 2-(4-Methoxybenzoyl)-N-phenyl- 2-(1,2,4-triazol-1-yl)thioacetamide  

作　　者：LIUFa-qian QINYong-qi LIWei-hua YANGShuang-hua LULu-de YANGXu-jie 

机构地区：[1]MaterialsChemistryLaboratory,NanjingUniversityofScienceandTechnology,Nanjing210094,P.R.China [2]CollegeofChemistryandMolecularEngineering,QingdaoUniversityofScienceandTechnology,Qingdao266042,P.R.China [3]CollegeofChemistryandChemicalEngineering,OceanUniversityofChina,Qingdao266033,P.R.China／／InstituteofOceanology,ChineseAcademyofSciences,Qingdao266071,P.R.China

出　　处：《Chemical Research in Chinese Universities》2005年第3期280-283,共4页高等学校化学研究（英文版）

摘　　要：The title compound, 2-(methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide was synthesized by several reactions from 4-methoxyacetophenone, triazole and phenyl isothiocyanate. The structure was identified by elemental analysis, ~ 1H NMR, MS and IR. The single crystal structure of 2-(methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide was determined with X-ray diffraction. The preliminary bioassays show that the title compound exhibits weak antifungal activities and plant-growth regulatory activity.The title compound, 2-(methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide was synthesized by several reactions from 4-methoxyacetophenone, triazole and phenyl isothiocyanate. The structure was identified by elemental analysis, ~ 1H NMR, MS and IR. The single crystal structure of 2-(methoxybenzoyl)-N-phenyl-2-(1,2,4-triazol-1-yl)thioacetamide was determined with X-ray diffraction. The preliminary bioassays show that the title compound exhibits weak antifungal activities and plant-growth regulatory activity.

关 键 词：1 2 4-Trizole THIOAMIDE Crystal structure Biological activities 

分 类 号：O623.626[理学—有机化学]